Games of the 8-, 16- & 32-bit era

Alien Syndrome

Title	Alien Syndrome
First release	1987
Developer	Sega
Publisher	Sega
Platforms	Amiga, Amstrad CPC, Atari ST, Commodore 64, DOS, Game Gear, MSX, Master System, NES / Famicom, ZX Spectrum, Arcade ADB
Genre	run and gun
Players	1–2 players
Co-op	Yes
ESRB rating	E Everyone
Releases	NES / Famicom: 1987-01-01 Amiga: 1988-01-01 MSX: 1988-01-01 ZX Spectrum: 1988-01-01 Master System: 1988-03-01 (NTSC-U) Amstrad CPC: 1988-12-01 Commodore 64: 1988-12-01 Atari ST: 1989-01-01
Wikidata ID	Q3273389

Navigate seven alien starships to rescue space colonists from extraterrestrial captors. Using flamethrowers and laser cannons, you must vaporize enemies and locate maps to traverse deadly levels. Each ship requires you to save all captives and defeat a powerful leader before you can progress to the next vessel.

Description: REG-Vault, CC BY-SA 4.0

View on Wikidata Read on Wikipedia

Facts from Wikidata (CC0), gaps filled from REG-Vault and TheGamesDB and Arcade Database (ADB). Only retro platforms tracked by this site are listed; the year is the earliest release date recorded on Wikidata.

Sources

Wikidata (Q3273389) · last updated 2026-09-27 · CC0

REG-Vault (gamegear/alien-syndrome) · last updated 2026-09-27 · descriptions CC BY-SA 4.0

REG-Vault (c64/alien-syndrome) · last updated 2026-09-29 · descriptions CC BY-SA 4.0

REG-Vault (amiga/alien-syndrome) · last updated 2026-09-27 · descriptions CC BY-SA 4.0

REG-Vault (nes/alien-syndrome) · last updated 2026-10-12 · descriptions CC BY-SA 4.0

REG-Vault (zxspectrum/alien-syndrome) · last updated 2026-10-02 · descriptions CC BY-SA 4.0

REG-Vault (amstradcpc/alien-syndrome-2) · last updated 2026-10-13 · descriptions CC BY-SA 4.0

TheGamesDB (1614) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (28807) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (6477) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (2973) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (24478) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (36564) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (38844) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (38081) · last updated 2026-07-18 · no licence stated · internal use only

TheGamesDB (11831) · last updated 2026-07-18 · no licence stated · internal use only

Arcade Database (ADB) (mt_asyn) · last updated 2026-10-02 · CC BY-NC-SA 3.0 · internal use only

Arcade Database ADB

MAME romset	`mt_asyn`
Title at ADB	Alien Syndrome (Mega-Tech, SMS based)
Manufacturer	Sega
Year	1987
Genre	Maze / Shooter Large
Players	2
MAME driver status	PRELIMINARY

Artwork: ADB (Arcade Database); artwork © original manufacturer (Sega); snaps by ProgettoSnaps via ADB. Non-free, internal use only (hotlinked, not downloaded).

Scraping using Arcade Database by motoschifo · CC BY-NC-SA 3.0 · romset via Wikidata P2451 (wikidata-qid) · fetched 2026-10-02 16:20 UTC · filled here: platform

Source: REG-Vault (upstream not stated) · © Sega · internal use only

1 / 34 Box art Box art (front) 1

Image credits

Box art, Screenshots, Logos, Artwork (24): Source: REG-Vault (upstream not stated) · © Sega · internal use only. REG-Vault page

Box art, Screenshots, Logos, Artwork (6): Source: TheGamesDB (user-uploaded) · © Sega · internal use only. TheGamesDB page

Screenshots (3): Source: libretro-thumbnails (upstream libretro-thumbnails (art by developers/publishers; see repo README)) · © Sega · internal use only.

Logo: Eigenes Werk, Public domain, via Wikimedia Commons (“AlienSyndrome.jpg”)

Sprites

No sprite sheets yet. Find sprites on The Spriters Resource ↗ /

Videos

Amiga 500 Longplay [271] Alien Syndrome

World-of-Longplays · Amiga version · longplay · 44:59auto-matched
Watch on YouTube ↗ · auto:channel-harvest, checked 2026-10-25 18:42 UTC

ALIEN SYNDROME (AMIGA - FULL GAME)

Zeusdaz - The Unemulated Retro Game Channel · Amiga version · longplay · 28:26auto-matched
Watch on YouTube ↗ · auto:channel-harvest, checked 2026-10-25 18:42 UTC

"Auto-matched" videos were found automatically (title + platform match via the YouTube Data API) and may occasionally be wrong. Videos are hosted by YouTube (embedded via youtube-nocookie.com; nothing loads from YouTube until you press play) and belong to their channels.